Cerevance Media Center

Current News

April 19, 2022

Cerevance Announces Leadership Transition to Implement Next Phase of Growth in Advancing Novel Therapeutics for Brain Diseases

Cerevance today announced the appointment of Craig Thompson to chief executive officer. Mr. Thompson brings over 25 years of commercial and marketing leadership experience in the biotech and pharmaceutical industries to the company.

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March 31, 2022

Cerevance Reports Positive Phase 2 Clinical Trial Results with CVN424, a Parkinson’s Disease Drug Working Through a New Mechanism

Cerevance today announced the completion of its Phase 2 clinical trial of CVN424, the company’s first-in-class, once-a-day, orally-delivered compound in development for the treatment of Parkinson’s disease.

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January 25, 2022

Cerevance Doses First Subjects in Phase 1 Clinical Trial of CVN766

Cerevance Doses First Subjects in Phase 1 Clinical Trial of CVN766

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September 8, 2021

Neuroscience Drug Development Veteran Mike Poole, M.D., FACP, to Join Cerevance Board of Directors

Cerevance today announced the appointment of Mike Poole, M.D., FACP, to Cerevance’s Board of Directors.

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News Archive

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July 10, 2023

Alzheimers Association International Conference

Date:
Monday, July 17, 2023
Time:
8:45am – 4:15pm
Location:
Amsterdam, Netherlands
Media:
Presentation
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June 28, 2023

XVI European Meeting on Glial Cells in Health and Disease

Date:
Monday, July 10, 2023
Time:
1:00pm – 4:00pm
Location:
Berlin, Germany
Media:
Poster
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June 26, 2023

Gordon Research Conference

Date:
Sunday, July 2, 2023
Time:
Various times through July 7
Location:
Les Diablerets, VD, Switzerland
Media:
Presentation
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Events Archive

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June 27, 2024

CryoEM Structure of the human THIK-1 K2P K+ Channel Reveals a Lower ‘Y-gate’ Regulated by Lipids and Anaesthetics

Rödström, K. E.J., Eymsh, B., Proks, P., Hayre, M. S., Madry, C., Rowland, A., Newstead, S., Baukrowitz, T., Schewe, M., Tucker, S. J.

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January 26, 2023

Scalable Synthesis of CVN424, an Inverse Agonist of the GPR6 Receptor

Mu, C., Li, X., Yang, Y., Zhou, Y., Wang, C., Doyle, K.J., Ye, N., Mistry, A., Burli, R.

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December 1, 2020

First-Time Disclosure of CVN424, a Potent and Selective GPR6 Inverse Agonist for the Treatment of Parkinson’s Disease: Discovery, Pharmacological Validation, and Identification of a Clinical Candidate

Sun, H., Monenschein, H., Schiffer, H.H., Reichard, H.A., Kikuchi, S., Hopkins, M., Macklin, T.K., Hitchcock, S., Adams, M., Green, J., Brown, J., Murphy, S.T., Kaushal, N., Collia, D.R., Moore, S., Ray, W.J., English, N.M., Carlton, M.B, Brice, N.L.

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February 26, 2024

Differential Contribution of THIK‑1 K+ Channels and P2X7 Receptors to ATP‑Mediated Neuroinflammation by Human Microglia

Rifat, A., Ossola, B., Bürli, R. W. , Dawson, L. A., Brice, N. L., Rowland, A., Lizio, M., Xu, X., Page, K., Fidzinski, P., Onken, J., Holtkamp, M., Heppner, F. L., Geiger, J. R. P., Madry, C.

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March 21, 2022

The Two Pore Potassium Channel THIK-1 Regulates NLRP3 Inflammasome Activation

Drinkall, S., Lawrence, C.B., Ossola, B., Russell, S., Bender, C., Brice, N.L., Dawson, L.A., Harte, M., Brough D.

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November 21, 2022

Pharmacological Targeting of Glutamatergic Neurons within the Brainstem for Weight Reduction

Schneeberger, M., Brice, N.L., Pellegrino, K., Parolar, L., Shaked, J.T., Page, K., Marchildon, F., Barrows, D., Carroll, T.S., Tolpiko, T., Mulligan, V., Barker, D., Glen, A., Newman, R., Ortuño, M.J., Renier, N., Nectow, A.R., Cohen, P., Carlton, M., Heintz, N., Friedman, J.M.

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