October 2, 2023

Cerevance Announces Presentation at the 36th European College of Neuropsychopharmacology Congress

What’s a Rich Text element?

The rich text element allows you to create and format headings, paragraphs, blockquotes, images, and video all in one place instead of having to add and format them individually. Just double-click and easily create content.

Static and dynamic content editing

A rich text element can be used with static or dynamic content. For static content, just drop it into any page and begin editing. For dynamic content, add a rich text field to any collection and then connect a rich text element to that field in the settings panel. Voila!

How to customize formatting for each rich text

Headings, paragraphs, blockquotes, figures, images, and figure captions can all be styled after a class is added to the rich text element using the "When inside of" nested selector system.

Boston, MA – October 2, 2023 – Cerevance, a private, clinical-stage drug discovery and development company focused on developing novel precision therapeutics for central nervous system (CNS) diseases using the company’s proprietary Nuclear Enriched Transcript Sort sequencing (NETSseq) platform, today announced a poster presentation at the 36th European College of Neuropsychopharmacology Congress (ECNP), taking place in Barcelona, Spain from October 7 – 10, 2023.

Presentation details

Title: CVN766: Selective Ox1R antagonist shows efficacy in pre-clinical models of schizophrenia

Overview: CVN766 is a potent and selective orexin 1 receptor antagonist with a desirable pharmacokinetic profile for CNS indications. In pre-clinical models, CVN766 demonstrated efficacy in models of schizophrenia across negative, positive, and cognitive symptomatology representing its potential as a novel therapeutic in this disease and other psychiatric conditions.

Session Date and Time: Monday, October 9 from 12:35 – 2pm CEST

About Cerevance

Cerevance is focused on the development of precision treatments for central nervous system (CNS) disorders, prioritizing chronic neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis (ALS). Utilizing a large and growing collection of over 14,000 human brain tissue samples, Cerevance is generating an unprecedented level of expression and epigenetic data thereby enabling the company to identify the most promising targets for the next generation of treatments for CNS disorders.

The company utilizes its proprietary NETSseq platform and advanced machine learning techniques to uncover the gene expression profiles of select cell types to identify novel targets that are uniquely expressed in relevant circuits affected by diseases or are altered in disease states. With the information obtained from its research, combined with the expertise of its team of scientists and drug developers, Cerevance is advancing multiple therapeutics that selectively modulate the discovered targets. These treatments are progressing through clinical development, with CVN424, CVN766, and CVN293 being the furthest along in the pipeline. CVN424 is a first-in-class non-dopamine therapy that shows promise in improving both motor and non-motor symptoms of Parkinson's disease and may also have disease-delaying effects. CVN766 is a potent antagonist of the orexin 1 receptor with high selectivity over the orexin 2 receptor which may benefit a variety of psychiatric conditions including schizophrenia, anxiety/panic, binge eating/obesity, substance use disorder, and Prader-Willi Syndrome. CVN293 is a novel blocker of potassium efflux in glia, regulating the inflammasome in individuals living with ALS and Alzheimer's disease.

By leveraging its extensive collection of brain tissue samples, employing advanced technologies, and generating actionable data, Cerevance aims to transform the lives of patients affected by CNS diseases.

Contacts 

Cerevance: 

Johnna Simoes, ir@cerevance.com

Media

Andrew Mielach, amielach@lifescicomms.com, +1-646-876-5868